Research studies

*If your team is seeking research support from CESPHN, please complete our document Support Request form (43 KB)  and return to our research intake officer for review.

The following is a list of research studies relevant to general practice. Please note that CESPHN has no direct involvement with anhy studies listed. Contact the specified contact person listed for each study for further information.

Referrals of migraine patients sought for new migraine prevention study

The George Institute for Global Health is conducting an NHMRC funded migraine prevention study and is inviting GPs to refer adult males and females aged 18-65 years with episodic migraine (2-14 days/month) and SBP >130mmHg OR DBP mmHg to be screened at one of the study sites at Royal Prince Alfred or Prince of Wales Hospitals.

The HeadAche Prevention Project (HAPPy trial) is testing whether migraine is prevented by blood preassure lowering or cholesterol lowering medications compared with standard therapy or placebo and has been approved by the Sydney Local Health District Human Research Ethics Committee (Ref: HREC/15RPAH/554). The study involves six visits over 20 weeks. The trial is grant funded but we are able to provide a nominal $30 reimbursement for GP time in making a referral. GPs will also receive a follow-up from the trial centre on their patient's participation.

For more information GPs can contact the HAPPy study Project manager Ruth Freed at rfreed@georgeinstitute.org.au and participants can visit http://headacheaustralia.org.au or call 1800 397 371.

New pathology test education

How GPs currently learn about the availability of new pathology tests for their patients and what are the most effective communication methods to alert GPs of new tests, are both poorly understood. This research aims to identify what methods are preferred by GPs when learning about new pathology tests.

A quick 10 question survey (2-3 mins) is being used to collect de-identified opinions from GPs about current and desired methods of communication regarding new pathology testing.

Click here to complete the survey.

PRO-E2 Study: Family Planning NSW

Do you prescribe the contraceptive pill? We need your help to recruit women in Australia in to an important, large, non-interventional, international study. Family Planning NSW is currently forming a network of doctors to recruit for the PRO-E2 study. The main outcome is the risk of venous thromboembolism. This is an exciting study that will provide "real world" data that may help to inform future practice. For more detials of how you can get involved email the research team or visit the website.

Survey: Inspire HCP GP medical education

InspireHCP is a medical education company focused on developing innovative GP continuing professional development (CPD) programs. We are conducting a survey to better understand GPs needs and how to improve their learning experience. If you are interested in shaping the future of GP education, fill in the survey, or contact us to find out more about our programs.

Survey: MotherSafe Questionnaire 2016

MotherSafe is a counselling service which provides evidence based information about exposures during pregnancy and breastfeeding.

As part of MotherSafe's commitment to research and continuing quality improvement, we would like to ascertain the current advice and recommendations of Australian medical practitioners and community pharmacists in relation to the scenarios outlined in a short questionnaire.

We hope to gain a better understanding of the types of advice GPs and pharmacists are currently giving to their pregnant or breastfeeding patients. Results of the survey will be incorporated and published as part of an educational service.

Please click to access our questionnaire.

Any queries should be directed to Susan Kwok or Joanna Broad (MotherSafe Counsellors), the Royal Hospital for Women on (02) 9382 6539.

Survey: Understanding and provision of preconception care by GPs

Preconception health focuses on taking steps now to protext the health of a baby in the future. As GPs are key to preventative healthcare provision we are interested in your thoughts, current practice and potential additional service or resource needs in the area. We intend that this research study will improve knowledge and provision of preconception care within the district. It will only take 5-10 minutes to complete and all responses are anonymous.

You may open the survey in your web browser by clicking the link below: 

Understanding preconception care

If the link above does not work, try copying the link below into your web browser. 

https://redcap.sswahs.nsw.gov.au/surveys/?s=AYFRMWFHE8

Participation in this study is entirely voluntary. You do not have to take part in it. Please note that by completing and submitting the survey, you will be indicating your consent to participate. If you do decide to participate but then change your mind before finishing the survey, simply close your web browser. The information you provide is completely confidential. Access to study information will be limited  to members of the research team only and no identifying information will appear in any publications or presentation.

The survey has been approved by the Ethics Review Committee (RPAH Zone) of the Sydney Local Health District. Any person with concerns or complaints about the conduct of the study should contact the Executive Officer on (02) 9515 and quote protocol number X15-0275. If you have any questions about the study, feel free to contact Dr Adrienne Gordon, RPAH or Dr Kyra Sim, The University of Sydney on (02) 8627 0403.

What do you think about mobile apps for obesity/inactivity?

Looking for GPs for a pilot study about mobile phone apps to treat inactivity/obesity. What are the issues, problems and possibilities? Participate by one-on-one interview (30 min) or group discussion (50 min) at your practice or convenient location. For details visit the website or contact Natalya Godbold, The University of Sydney (Protocol Number 2016/221)

The CONNECT Study: A consumer-focused e-health strategy for cardiovascular risk management in primary care

CONNECT is a randomised, controlled trial that aims to assess whether a consumer focused e-health strategy provided to people at moderate to high risk of cardiovascular disease (CVD) event will improve risk factor control when compared with usual health care. It is funded by the National Health and Medical Research Council (NHMRC) and managed by The George Institute for Global Health.

CONNECT will provide suitable patients with a secure web app that is integratedwith their health service record. This information is presented in an easy to understand way so clients can see their personal risk of vardiovascular disease and provide them with strategies to lower their risk. It provides handy features such as assistance with personal goal setting and tracking, information on risk factors and medications, healthy tips and a community forum.

The study is designed to be of minimal burden to GPs and practice staff. GPs will receive 40 category 1 CPD points and $50 per participant recruited into the study.

If you would like more information about the CONNECT study please contact:

John Mulley - Senior Project Officer, The George Institute, Phone: (02) 9993 4524. Visit the Connect website.

SpringBoarD project: Trial of a self-help intervention to improve functioning and wellbeing in people with type 2 diabetes

The emotional toll of diabetes can make it hard for patients to reach their treatment targets, and the health consequences of poorly managed diabetes are significant. Using funding provided by the NHMRC, researchers at Sydney's Black Dog Institute, UNSW Australia and the University of Melbourne are studying whether an online self-help Cognitive Behavioural Therapy program can provide emotional support to people with type 2 diabetes; thereby helping them lead happier and healthier lives.

General practices in NSW and VIC are invited to take part in the project, called SpringboarD. Designed to minimise interruption to daily practice activity, this is an exciting opportunity for practices to get involved in eMental health; conveniently, easily and at no cost.

For each patient recruited to the study, practices will be reimbursed $50.

To learn more or get involved, send an email, call (02) 9382 8310, visit the SpringboarD website or download the GP information sheet.

New clinical trial on weight loss dietary supplements

A new clinical trial has commenced at the Boden Institute, University of Sydney. The trial involves a 6-month weight intervention  followed by a 6-month weight maintenance phase. The study will evaluate the efficacy of two dietary supplements: FBCx and Compound K on glucose control and weight loss. FBCx and Compound K on glucose control and weight loss. FBCx is a dietary fibre supplement derived from corn that has the ability to bind to and prevent the absorption of dietary fat more efficently than other known dietary fibres. Compound K is a ginseng derivative that has been shown to have antidiabetic properties and may assist with blood glucose control.

Participating patients will receive: 

  • Ongoing dietetic and exercise counselling administered by qualified allied health professionals for 12 months.
  • Body composition assessments using Dual-energy X-ray absorptiometry (DEXA)
  • Regular blood tests which are reviewed by an endocrinologist
  • ECG exam which is reviewed by a medical officer
  • Grocery cards to thank them for their participation

Participating GPs will receive reports about progress of their participating patients at six and 12 months.

The main inclusion criteria for patients are to have pre diabetes, BMI>kg/m2  and not on cholesterol lowering medication.

If you would like more information about the trial or would like to refer patients please contact Dr Claire Madigan on 8627 1990 or claire.madigan@sydney.edu.au.

document Click here (104 KB) to download the information statement.

Novel Quit-Smoking Trial

Do you have patients who want to shake off nicotine addiction but who can't find the motivation? Consider a referral for a novel method developed by a team of smoking cessation specialists at the University of Sydney, led by Chief Investigator Professor Geoffery Tofler. We know that an illness episode can provide a "teachable moment", when health knowledge ceases to be purely cognitive and becomes felt and personal. A heart attack is one such moment which can galvanise patients into ceasing smoking. Our technique simulates this teachable moment with a personalised video which portrays a heart attack from the point of view of the individual smoker.

Our trial will compare a personalised video, plus conventional treatment, with a non-personalised video, plus conventional treatment. Subjects will attend the Croydon Community Centre for the viewing, and we will also offer patient education, and supportive and cognitive-behavioural therapy. NRT is encouraged but is left to patient and doctor.

We invite GPs to identify potential subjects and to contact us. Special interest GPs who are interested in conducting the study in their own rooms should also contact us.

The study is supported by Dr Michael Moore, Dr Colin Mendelsohn, and Associate Professor Renee Bittoun.

For enquiries, please contact Mr Robin May, Study Co-ordinator, phone: 9462 9177

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